actualiteitsforums  

Ga Terug   actualiteitsforums > ACTUALITEITSFORUM > WERELD > Wetenschap
Gebruikersnaam
Wachtwoord
Home FORUMS Registreer Arcade Zoeken Posts van vandaag Markeer Forums als Gelezen

Antwoord
 
Onderwerp Opties Zoek in onderwerp Waardeer Onderwerp Weergave Modus
  #1  
Oud 16th November 2006, 20:49
Barst's Avatar
Barst Barst is offline
Administrator
 
Geregistreerd op: Jun 2004
Locatie: L'burg
Posts: 16,562
Natural-born painkiller found in human saliva

Natural-born painkiller found in human saliva


Saliva from humans has yielded a natural painkiller up to six times more powerful than morphine, researchers say.


The substance, dubbed opiorphin, may spawn a new generation of natural painkillers that relieve pain as well as morphine but without the addictive and psychological side effects of the traditional drug.

When the researchers injected a pain-inducing chemical into rats’ paws, 1 milligram of opiorphin per kilogram of body weight achieved the same painkilling effect as 3 milligrams of morphine.

The substance was so successful at blocking pain that, in a test involving a platform of upended pins, the rats needed six times as much morphine as opiorphin to render them oblivious to the pain of standing on the needle points.


Anti-depressive angle

“Its pain-suppressive effect is like that of morphine,” says Catherine Rougeot at the Pasteur Institute in Paris, France, who led the research. “But we have to test its side effects as it is not a pure painkiller,” she says. “It may also be an anti-depressive molecule.”

Rougeot and colleagues discovered that opiorphin works in nerve cells of the spine by stopping the usual destruction of natural pain-killing opiates there, called enkephalins.

Opiorphin is such a simple molecule that it should be possible to synthesise it and produce large quantities without having to isolate it from saliva, Rougeot explains. Alternatively, it might be possible to find drugs which trigger patients’ bodies to produce more of the molecule themselves.

Journal reference: Proceedings of the National Academy of Sciences (vol 103, p 17979)


NewScientist.com news service, 13-11-2006
__________________
"Never argue with an idiot, they'll just bring you
down to their level and beat you with experience." (c)TB
Met citaat antwoorden
Antwoord


Onderwerp Opties Zoek in onderwerp
Zoek in onderwerp:

Uitgebreid Zoeken
Weergave Modus Stem op dit onderwerp:
Stem op dit onderwerp::

Posting Regels
Je mag niet nieuwe onderwerpen maken
Je mag niet reageren op posts
Je mag niet bijlagen posten
Je mag niet jouw posts bewerken

vB code is Aan
Smilies zijn Aan
[IMG] code is Aan
HTML code is Uit
Forumsprong



Alle tijden zijn GMT +2. De tijd is nu 01:51.


Powered by: vBulletin Version 3.0.6
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.